Highly efficient carbazolyl-derived phosphine ligands: application to sterically hindered biaryl couplings.
نویسندگان
چکیده
A new family of phosphine ligands bearing a bulky carbazolyl scaffold is described. With the combination of ligand 2a and Pd(OAc)(2), difficult tri-ortho-substituted biaryl couplings are accomplished smoothly. In particular, the catalyst loading as low as 0.02 mol% of Pd for non-activated 2,6-disubstituted aryl chloride coupling can be achieved.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 17 شماره
صفحات -
تاریخ انتشار 2011